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Job Opportunity: Laboratory Research Scientist:Job description:Job location: London Job location: The Francis Crick Institute, Midland Road, London Contract: Fixed term for 2 years, Full time Short summary We are pursuing an enthusiastic and proactive Laboratory Research Scientist to join a world-leading laboratory working on the sensing and signalling of oxygen levels in cells. The work has broad relevance in biology and direct relevance to many or most human diseases, including heart and lung disease, stroke and cancer. The laboratory is ?problem-located' and deploys a very wide variety of technologies to address these problems. more information can be found about the group at https://www.crick.ac.uk/research/labs/peter-ratcliffe Key Responsibilities These include but are not limited to: » Provision of technical and research support in the area of hypoxic cell biology including the tissue culture of significant specialised cells » Preparation and analysis of samples for proteomic mass spectrometry (MS), including discovery and targeted MS analyses » Contribute to the development of assays of oxygen sensitivity in cultured cells including fluorescence microscopy » Performance of cell engineering under the direction and supervision of senior laboratory staff » Compliance with all regulatory and safety protocols » Accurate organisation of work and experimental record keeping practice and Competencies The post holder should embody and demonstrate our core Crick values: Bold; Open; Collegial Essential » BSc or MSc in biochemistry, cell biology or related discipline » Good working knowledge of general molecular biology techniques including tissue culture » capability to work accurately and maintain good records » Strong collaborative capability and teamwork practice Desirable » practice in protein mass spectrometry » practice in genetic engineering of cells » practice in fluorescence microscopy About us The Francis Crick Institute is a biomedical discovery institute dedicated to knowledge the fundamental biology underlying health and disease. Its work is helping to understand why disease develops and to translate discoveries into new ways to prevent, diagnose and treat illnesses such as cancer, heart disease, stroke, infections, and neurodegenerative diseases. An independent organisation, its founding partners are the Medical Research Council (MRC), Cancer Research UK, Wellcome, UCL (University College London), Imperial College London and King's College London. The Crick was formed in 2015, and in 2016 it moved into a new state-of-the-art building in central London which brings together 1500 scientists and support staff working collaboratively across disciplines, making it the biggest biomedical research facility under in one building in Europe. The Francis Crick Institute will be world-class with a strong national function. Its distinctive vision for excellence includes commitments to collaboration; developing emerging talent and exporting it the rest of the UK; public engagement; and helping turn discoveries into treatments as quickly as possible to improve lives and strengthen the economy. » If you are interested in applying for this function, please apply via our website. » The closing date for applications is 19 May 2024. » All offers of employment are subject to prosperous security screening and continuous eligibility to work in the United Kingdom. Skills:
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