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Offer: Postdoctoral Research Associate:Job description:Job location: York Research Associate in Parasite Biology function Applications are invited for a postdoctoral researcher for 36 months (potential extension up to 54 months) to execute laboratory-located research on theLeishmaniaparasite within the Department of Biology. The prosperous candidate will join a large team ofparasite biologistswithin theYork Biomedical Research Institute. The position is funded by a Wellcome Trust Career Development Award toDr. Nicola Bakerwho will manage the post. The project aims to uncover howLeishmania mexicanasense the pH and temperature changes that they encounter all over their lifecycle, with a focus on protein kinases. Large scale screens, including use of a previously generated mutant library (Baker et al. 2021), will identify kinases of interest. The postholder will use a combination of proteomic (proximity labelling and phosphoproteomics) and molecular techniques (western blotting, microscopy and phenotypic assays) to interrogate parasite signalling pathways and identify sensors. This post will therefore suit someone with a PhD in a significant area who can bring proteomic and mass spectrometry skills. Previous practice in cell culture of Class 2 pathogens and general molecular biology techniques is also desirable. Department Our laboratories provide a supportive and collaborative environment in which the postdoctoral researcher can expand their range and lgain new techniques. The Department of Biology is renowned internationally for its research, including biomedical research within the York Biomedical Research Institute. We strive to provide a working environment which allows all staff and students to contribute fully, flourish, and excel. We aim to ensure that there is a supportive and egalitarian culture across all staff, groups and levels. We promote good practice and a strong culture of equality in higher education. more information can be found on our website. Skills, practice & Qualification needed » A PhD in Molecular Biology, Protein Biochemistry or related area. » expertise of proteomic methods » practice in cutting edge proteomic techniques, including analysis. » Skills and practice in gene editing are desirable. » practice in cell culture, and in handling of class 2 pathogens are desirable. » Competency to conduct individual and collaborative research projects. this function is available on a fixed term basis for up to 36 months. Interview date: To be confirmed . For informal information: Contact Us by Dr. Nicola Baker on nicola.baker@york.ac.uk The University strives to be diverse and inclusive - a place where we can ALL be ourselves. We particularly encourage applications from people who identify as Black, Asian or from a Minority Ethnic background, who are underrepresented at the University. We offer family friendly, flexible working arrangements, with forums and inclusive facilities to support our staff.#EqualityatYork Skills:
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