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Job Opportunity: Postdoctoral Researcher:Job description:Job location: Oxford About the function We are seeking for an academically driven postdoctoral researcher to join our interdisciplinary team, exploring how fibroblast cues regulate fibrotic niches in the human and mouse intestine. You will be applying a range of molecular biology techniques (e.g., single cell/spatial transcriptomics & proteomics) to profile patient cohort samples and mouse tissues, conduct and analysein vivomouse models, develop and deploy mechanistic tissue organoid assays, and carry out integrative bioinformatic analyses. Besides your project responsibilities, you will become an integrative part of the research group, supporting the team in a wide variety of experimental approaches and with topical skills. You will contact with your direct manager, and other members of group, regarding experiments and general laboratory procedures. About You candidates must hold a PhD in a significant subject, or be close to completion. You will also need to demonstrate that you have: • An capability to independently manage own research and administrative activities. • practice of following, adapting and generating experimental and analytic protocols. • Hands-on practice ofin vivomouse models. • An excellent knowledge of intestinal immunity. • A keen interest in the pathophysiology of inflammatory bowel disease and intestinal fibrosis. • Excellent communication skills, including the capability to write text that can be published, and present data at meeting. Having skills in cutting-edge bioinformatic analysis and having an expert knowledge of fibrosis pathomechanisms would both be desirable attributes for this post. Translational Gastroenterology and Liver Unit The Translational Gastroenterology and Liver Unit (TGLU) is situated in the John Radcliffe Hospital and headed by Paul Klenerman. The Unit builds on excellent clinical programmes in inflammatory bowel disease and hepatology as well as cutting edge basic science programmes in mucosal immunology. The new state of the art laboratories are in close proximity to clinical gastroenterology and bring together scientists, clinician scientists and gastroenterologists with the objective of translating fundamental research in mucosal immunology into enhanced treatments for inflammatory bowel disease, liver disease and cancer. For more information please visit: https://www.expmedndm.ox.ac.uk/tgu What We Offer: • An excellent contributory pension scheme • 38 days annual leave • A comprehensive range of childcare services • Family leave schemes • Cycle loan scheme • Discounted bus travel and Season Ticket travel loans • Membership to a variety of social and sports clubs Seehttps://hr.admin.ox.ac.uk/staff-benefitsfor more information. Application Process: We are committed to equality and valuing diversity. The post is full-time and fixed-term for 3 years. Applications for this vacancy are to be made online. You will be required to upload a supporting statement (maximum 2 pages) and CV as part of your online application. Only applications received before 12:00 midday on 23/05/2024 will be considered. Interviews are due to take place on the week commencing 03/06/2024. Skills:
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